The table below shows the US GAAP Pretax Income (Loss) From Continuing Operations for the first quarter of both 2020 and 2019 for each of these 41 San Diego Area Companies.
| US | US | |||
| GAAP | GAAP | |||
| Pretax | Pretax | |||
| Income | Income | |||
| (Loss) | (Loss) | Better | ||
| First | First | (Worse) | ||
| Quarter | Quarter | % | ||
| San Diego Largest Companies | 2020 | 2019 | Change | |
| Market Caps Above $1 Bil | City HQs | mils $ | mils $ | |
| Qualcomm | San Diego | 598 | 806 | |
| Illumina | San Diego | 178 | 233 | |
| DexCom Inc | San Diego | 22 | (27) | |
| Sempra Energy | San Diego | 397 | 501 | |
| ResMed | San Diego | 192 | 138 | |
| Realty Income Corp | San Diego | 147 | 111 | |
| Neurocrine Biosciences | San Diego | 39 | (103) | |
| Quidel | San Diego | 49 | 27 | |
| Ionis Pharmaceuticals | Carlsbad | (62) | 122 | |
| ACADIA Pharmaceuticals | San Diego | (88) | (85) | |
| LPL Financial Holdings | San Diego/ Boston, MA | 208 | 204 | |
| Tandem Diabetes Care | San Diego | (15) | (23) | |
| Mirati Therapeutics | San Diego | (87) | (41) | |
| Arena Pharmaceuticals | San Diego | (100) | 730 | |
| ICU Medical | San Clemente | 20 | 33 | |
| Halozyme Therapeutics | San Diego | (6) | 2 | |
| Fate Therapeutics | San Diego | (34) | (20) | |
| NuVasive Inc | San Diego | 10 | 11 | |
| WD-40 Company | San Diego | 17 | 20 | |
| Turning Point Therapeutics | San Diego | (61) | (14) | |
| ViaSat Inc | Carlsbad | 6 | (0) | |
| Teradata | San Diego/ Dayton, OH | (14) | (10) | |
| AMN Healthcare Services | San Diego/ Dallas, TX | 25 | 39 | |
| Kratos Defense & Security Solutions | San Diego | (1) | 2 | |
| Ligand Pharmaceuticals | San Diego | (30) | 843 | |
| Heron Therapeutics | San Diego | (52) | (63) | |
| PriceSmart | San Diego | 38 | 36 | |
| American Assets Trust | San Diego | 15 | 15 | |
| CareTrust REIT Inc | San Clemente | 19 | 16 | |
| Glaukos Corp | San Clemente | (55) | (1) | |
| Jack in the Box | San Diego | 17 | 34 | |
| MaxLinear Inc | Carlsbad | (22) | (11) | |
| Callaway Golf Co | Carlsbad | 38 | 58 | |
| Cubic Corp | San Diego | (72) | (13) | |
| Retail Opportunity Investments Corp | San Diego | 13 | 15 | |
| Sorrento Therapeutics | San Diego | (69) | (146) | |
| Axos Financial | San Diego/ Las Vegas/ NV | 80 | 54 | |
| Encore Capital Group | San Diego | (6) | 53 | |
| Retrophin | San Diego | (18) | (41) | |
| Avidity Bioscience | La Jolla | (6) | (3) | |
| Gossamer Bio | San Diego | (54) | (33) | |
| Total all 41 San Diego Area Cos | 1,276 | 3,469 | -63% |
